P-75: The Association of Antiphospholipid Syndrome and Recurrent Miscarriages

نویسندگان

  • MR Ranjouri Student Research Comittee, Medical Genetic Department, Faculty of Medicine, Zanjan University of Medical Science, zanjan, Iran
  • P Aob Student Research Comittee, Medical Genetic Department, Faculty of Medicine, Zanjan University of Medical Science, zanjan, Iran,
چکیده مقاله:

a:4:{s:10:"Background";s:364:"Antiphospholipid syndrome is a coagulation disorder that causes recurrent miscarriages and fetal deaths. In the present review we summarize current knowledge about Antiphospholipid syndrome that associated with recurrent miscarriages. In addition, on the basis of these comprehensive data, possible pathophysiologic mechanisms of this disorder are discussed.";s:19:"MaterialsAndMethods";s:223:"We searched PubMed using keywords such as “Antiphospholipid Syndrome” and “Recurrent Miscarriages” for articles with significantly high citation that published from 2005 to 2014 and totally 23 articles were used.";s:7:"Results";s:770:"Sixty percent of recurrent spontaneous abortions are unexplained. Antiphospholipid (Hughes) syndrome (APS) is a multisystem disease with the predominant features of venous and arterial thrombosis, recurrent pregnancy loss, fetal death and the presence of antiphospholipid antibodies. Many epidemiological studies focus on antiphospholipid syndrome as a cause of recurrent spontaneous abortion. Researchers have found that having antiphospholipid syndrome can increase women's chances of recurrent miscarriages. They believe that antiphospholipid syndrome causes blood clots to block the blood supply to the placenta. Others believe that having antiphospholipid syndrome may interfere with the fertilized egg’s ability to implant in the lining of the uterus.";s:10:"Conclusion";s:546:"There is accumulating evidence that recurrent miscarriages are associated with APS. Also, many studies demonstrate that thrombosis is observed frequently in the placentas of patients with antiphospholipid syndrome. However, published data showed no correlation between the severity of the disease (the number of previous miscarriages) and the prevalence of antiphospholipid antibodies and that these antibodies were also present in normal women. This review explains that women with APS are at increased risk of Recurrent pregnancy loss.";}

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Detection of multiple annexin autoantibodies in a patient with recurrent miscarriages, fulminant stroke and seronegative antiphospholipid syndrome

Anti-phospholipid syndrome (APS) is one of the main causes for recurrent miscarriages. The diagnosis of APS is based on the occurrence of clinical symptoms such as thrombotic events or obstetric complications as well as the detection of antiphospholipid antibodies directed against β2-glycoprotein I and cardiolipin, or a positive lupus anticoagulant assay. However, there is a subpopulation of pa...

متن کامل

Recurrent brachiocephalic vein thrombosis in antiphospholipid syndrome

We present a case of a middle-aged man with recurrent brachiocephalic vein thrombosis concomitant with antiphospholipid syndrome. The reported case concerns unique involvement of the brachiocephalic vein and the difficulties in laboratory diagnostics of the antiphospholipid syndrome.

متن کامل

Genetic causes of recurrent miscarriages.

Recurrent miscarriage is an important problem in reproductive health, which affects 1-5% of couples. The aim of this article is to summarize current knowledge on the genetic causes of recurrent miscarriage. It presents the most common parental genetic disorders (karyotype abnormalities, recessive diseases carrier status, dominant diseases and thrombophilia) connected with recurrent pregnancy lo...

متن کامل

existence and approximate $l^{p}$ and continuous solution of nonlinear integral equations of the hammerstein and volterra types

بسیاری از پدیده ها در جهان ما اساساً غیرخطی هستند، و توسط معادلات غیرخطی ‎‏بیان شد‎‎‏ه اند. از آنجا که ظهور کامپیوترهای رقمی با عملکرد بالا، حل مسایل خطی را آسان تر می کند. با این حال، به طور کلی به دست آوردن جوابهای دقیق از مسایل غیرخطی دشوار است. روش عددی، به طور کلی محاسبه پیچیده مسایل غیرخطی را اداره می کند. با این حال، دادن نقاط به یک منحنی و به دست آوردن منحنی کامل که اغلب پرهزینه و ...

15 صفحه اول

association of inherited thrombophilia and antiphospholipid syndrome with severe preeclampsia

background: severe preeclampsia is a quite well-known entity with high incidence of both maternal and fetal morbidity and mortality. although little is known about its etiology, inherited disorders of hemostasis and antiphospholipid syndrome have been postulated as common causes. the present study was conducted to evaluate the association of these two entities with preeclampsia in a group of ir...

متن کامل

منابع من

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ذخیره در منابع من قبلا به منابع من ذحیره شده

{@ msg_add @}


عنوان ژورنال

دوره 9  شماره 2

صفحات  74- 75

تاریخ انتشار 2015-09-01

با دنبال کردن یک ژورنال هنگامی که شماره جدید این ژورنال منتشر می شود به شما از طریق ایمیل اطلاع داده می شود.

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2023